And what is about the possibility of sporadic mutations- transmission of the disease gene? There is the explanation from Dr.Murphy (President of the International Committee on the Taxonomy of Viruses), he says;
„Recent research has shown that the scrapie PrP protein differs from the BSE PrP protein at only seven amino acid loci, whereas the BSE PrP protein differs from the human CJD PrP at more than 30 loci. These differences explain the concept of strains and help explain why prions from one species might jump more easily into another species than another. It is difficult to find the terms to discuss prions — for example, can we talk about mutants when there is no DNA? What would Watson and Crick think of all this?