Bradykinin potentiating peptides (BPPs) isolated from the venom of the snake, Bothrops jararaca increase both the duration and magnitude of bradykinin’s (Nonapeptide found in the blood plasma of animals after injection of venom) effects on vasodilation and the consequent fall in blood pressure1.
BPPs were discovered in partially purified preparations of Bothrops jararaca venom by their ability to increase bradykinin activity in vitro in guinea pig ileum and in vivo in rats1.