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brain cranial nerves

Scientists have discovered that a protein called BAG2 is important for understanding Alzheimer's and may open up new targets for treatment. They are ready to move from studying these proteins in culture to finding out how they work with mice.

The image depicts the cranial nerves of a normal human brain.

The protein tau is normally found in brain cells, but scientists don't know why it clumps into tangles in people with Alzheimer's.

The research team recently started to work on BAG2 to find out how it may be involved in the removal of tangled tau. "It turns out that when you put this protein into the cell, it clears away the damaged tau very nicely.  It doesn't clear away all the tau; it goes for the damaged tau protein and removes it.”

This is a protein that is involved in neurofibrillary tangles, so now we have a new target for treatment discovery. This is not a treatment, just a new target. The new target is BAG2