The attack began as Haqqani Network fighters launched rockets and mortars at a small US base in the Zarok district in Paktika province. As the rockets and mortars were fired, a suicide bomber attempted to ram a truck packed with explosives into the combat outpost, but soldiers shot and killed the driver before he could penetrate the base. The attackers also fired assault rifles and machine guns during the assault.

Reports indicate that two US soldiers were killed during the attack. Quqnoos claimed the soldiers were killed when the suicide bomber detonated at the main gate. Other reports indicated the soldiers were killed during the mortar attack. The US military stated that two soldiers were killed during an IED attack, but it is unclear if they were killed during the attack on the base.