
For years, scientists struggled to identify an adaptive advantage that might explain schizophrenia’s persistence. Researchers from various disciplines volleyed ideas back and forth. Some argued that the genes implicated in the disease promoted creativity; others believed that schizophrenics were frustrated cult leaders—unorthodox thinkers constitutionally “engineered” to lead segments of humanity to break off from the herd, but who lacked the charisma to effect much change. None of the theories gained much traction.